Diagnostic Accuracy of Ultrasound in Correlation to Alkaline Phosphatase Levels in Patients with Biliary Obstructions

Ultrasound & Alkaline Phosphatase Levels in Biliary Obstructions

Abstract

Abdominal Ultrasonography (USG) is an appropriate initial screening method for detection of biliary tract disease the consultants sometimes encounter patients who only have findings of dilatation of the Common Bile Duct (CBD) on US without specific biliary symptoms or jaundice.

Objective: To determine the diagnostic accuracy of ultra sound in correlation to alkaline phosphatase levels in patients with billiary obstructions.

Methods: Total 100 patients were selected during 6 months. Data were tabulated and analyzed by SPSS version 24.0. The quantitative variables were presented in form of mean± S.D and Chi square test was used to test the association between categorical variables. A semi-structured questionnaire was prepared and finalized after pre-testing.

Results: 59 (0.59%) females and 41 (0.41%) males. 63 (0.63%) patients presented with abdominal pain. 85(0.85%) have CBD, 64 (0.64%) has stones as common cause of obstruction. The mean scoring of Alkaline Phosphate Level (APL) was 439.9 9+10.54. There was significant association between the age groups and cause of obstruction in patients, gender and complaints of patients (pvalue < 0.05).

Conclusions: A significant number of causative biliary tract lesions in asymptomatic adults with dilatation of the CBD on routine abdominal US; no laboratory or demographic parameters were useful for discrimination.