Frequency of Contrast Induced Nephropathy After Coronary Angiographic Procedure

Frequency of Contrast Induced Nephropathy

Abstract

Contrast media is increasingly used in investigative and interventional processes, resulting in the increasing incidence of iatrogenic renal function damage caused by the exposure to contrast media, a state known as Contrast Induced Nephropathy.

Objective: To determine the frequency of Contrast Induced Nephropathy after Coronary Angiographic procedure. Methods: A study involving 105 patients was arranged to determine the effect of contrast media after coronary angiography. Data were analyzed using SPSS Version 21.0. Paired sample t-test was used to determine the significance.

Results: Mean age of patients was 52.27±12.73years, 26(24.76%) were females and 79 (75.24%) were males. There were total 105 patients, 73 (32.6%) had hypertension and 45(20.1%) were smokers. Diabetes mellitus was present in 48(21.4%) patients, 13(5.8%) had chronic renal failure, 39 (7.4%) had strong family history of existing disease. Ionic dye was used in 24(22.86%) patients and in 81(77.14%) patients non-ionic dye was used. The mean value of pre procedural urea was 33.87±15.39 and after procedure was 46.70±30.49 with the significant increment, p-value<0.001.The mean and S.D values of Creatinine before and after procedure was 0.95+ 0.42 and 1.23±0.70 respectively, it means creatinine was signicantly increased after procedure, p-value ><0.001. Conclusions: It was concluded that highly signicant results> < 0.0001.

Conclusion: It was concluded that highly significant result for contrast induced nephropathy exist with the change in value of urea and creatinine and risk factors like hypertension, diabetes mellitus and chronic renal failure and family history of existing heart disease.